Mupir-5g

Mechanism of Action (MOA):

Mupirocin works by inhibiting bacterial protein synthesis. It specifically and reversibly binds to bacterial isoleucyl transfer-RNA (tRNA) synthetase, an enzyme essential for protein and RNA synthesis in bacteria. This inhibition leads to the cessation of bacterial growth and replication.

Dosage and Administration:

• Application: Clean and dry the affected area before applying the ointment. Apply a small amount to the affected area 3 times a day. A dressing can be applied over the treated area if needed.
• Duration: Continue treatment for the duration prescribed by your healthcare provider, typically up to 10 days.

Side Effects:

• Common Side Effects:
  • Burning or stinging sensation at the application site
  • Itching
  • Redness
  • Dryness
• Serious Side Effects:
  • Severe allergic reactions, including anaphylaxis, urticaria, angioedema, and generalized rash
  • Clostridium difficile-associated diarrhea (CDAD)

If any serious side effects occur, discontinue use and consult a healthcare professional immediately.

Drug Interactions:

Mupirocin is applied topically and has minimal systemic absorption, leading to a low potential for drug interactions. However, avoid using other topical products on the same area unless advised by a healthcare provider.

Precautions:

• Allergic Reactions: Discontinue use if a severe allergic reaction occurs and seek medical attention.
• Eye Contact: Avoid contact with eyes. In case of accidental contact, rinse well with water
• Infection Persistence: If the infection persists or worsens after 3 to 5 days of treatment, consult a healthcare provider.
• Use in Children: Safety and efficacy in children under 2 months of age have not been established.