Zoryl-M 2

• Zoryl-M 2 Tablet PR is an oral antidiabetic medication combining two active ingredients: glimepiride (2 mg) and metformin (500 mg extended-release). It is primarily prescribed for the management of Type 2 diabetes mellitus, aiming to improve blood sugar control in adults.

Mechanism of Action:

• Glimepiride: A sulfonylurea that stimulates the pancreas to release insulin, thereby lowering blood glucose levels.

• Metformin: A biguanide that decreases hepatic glucose production, delays intestinal glucose absorption, and enhances insulin sensitivity in peripheral tissues.

Dosage and Administration:

The initial recommended dose is one tablet once daily, taken with breakfast or the first main meal. Dosage adjustments should be individualized based on the patient’s response and tolerance, with regular monitoring of blood glucose levels.

Common Side Effects:

• Hypoglycemia (low blood sugar)
• Nausea
• Diarrhea
• Abdominal pain
• Metallic taste

• Dizziness

If any side effects persist or worsen, it is important to consult a healthcare professional.

Precautions:

• Kidney Disease: Use with caution; dose adjustments may be necessary. Regular monitoring of kidney function is advisable.
• Liver Disease: Use with caution; dose adjustments may be necessary. Regular monitoring of liver function is advisable.
• Pregnancy and Breastfeeding: Consult your doctor before use, as the medication may not be safe during pregnancy or breastfeeding.

• Alcohol Consumption: Avoid alcohol, as it may increase the risk of side effects such as drowsiness, dizziness, and impaired judgment.

Drug Interactions:Inform your doctor about all medications and supplements you are taking to prevent potential interactions. Zoryl-M 2 Tablet PR may interact with other drugs, affecting blood sugar control or increasing the risk of adverse effects.

Lifestyle Considerations:Maintain a balanced diet, engage in regular physical activity, and monitor blood sugar levels as directed. These lifestyle modifications are essential for effective diabetes management alongside medication.

Storage:Store in a cool, dry place away from light and moisture. Keep out of reach of children.

Always follow your doctor’s instructions regarding dosage and administration to achieve optimal blood sugar control and minimize the risk of complications.