Mozart-AM
₨ 195.00
- Brand Name: Mozart-AM
- Manufacturer: Magnus Pharma Pvt. Ltd.
- Generic Name: Losartan Potassium 50mg and Amlodipine 5mg
- Class of Drug: Antihypertensive Combination
- Dose: Each tablet contains 50 mg of Losartan Potassium and 5 mg of Amlodipine
- Use: Treatment of hypertension (high blood pressure) and hypertension with left ventricular hypertrophy (LVH)
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Mechanism of Action (MOA):
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Losartan Potassium: An Angiotensin II Receptor Blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, leading to vasodilation and reduced blood pressure.
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Amlodipine: A calcium channel blocker that inhibits the movement of calcium ions across cell membranes in systemic and coronary vascular smooth muscle, resulting in vasodilation and decreased blood pressure.
Dosage and Administration:
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Hypertension: The recommended starting dose is one tablet (50 mg Losartan Potassium and 5 mg Amlodipine) taken orally once daily. Dosage may be adjusted based on individual patient response.
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Hypertension with LVH: The same dosing regimen applies. Regular monitoring of blood pressure and cardiac function is advised.
Side Effects:
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Common Side Effects:
- Dizziness
- Headache
- Swelling of the ankles or feet (peripheral edema)
- Fatigue
- Flushing
- Palpitations
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Serious Side Effects:
- Low blood pressure (hypotension)
- Elevated potassium levels (hyperkalemia)
- Kidney dysfunction
- Angioedema (swelling of the face, lips, tongue, or throat)
If any serious side effects occur, seek medical attention promptly.
Drug Interactions:
- Potassium Supplements and Salt Substitutes: May increase the risk of hyperkalemia.
- NSAIDs: Concurrent use may reduce the antihypertensive effect and impair renal function.
- Lithium: Co-administration can lead to increased lithium levels and potential toxicity.
Inform your healthcare provider of all medications and supplements you are taking to avoid potential interactions.
Precautions:
- Pregnancy: Contraindicated during pregnancy due to potential risks to the developing fetus.
- Lactation: Not recommended; consult a healthcare provider.
- Renal and Hepatic Impairment: Use with caution; dose adjustments may be necessary.
- Volume-Depleted Patients: Initiate therapy with caution to prevent symptomatic hypotension.
Regular monitoring of blood pressure, kidney function, and electrolytes is recommended during treatment.
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